Immunoassay Development Scientist - Analyte Detection

We are seeking for hands-on immunoassay developers for a new Analyte Detection Business Unit. If you have designed assays from scratch, selected and screened reagent pairs, and solved real development problems across ELISA, MSD, TR-FRET, AlphaLISA, or related formats, we want to hear from you. Here’s what you’ll do:

Laboratory Execution & Technical Support

• Design and execute bioconjugation strategies for labeling antibodies and other proteins with donor/acceptor fluorophores (NHS-ester, maleimide, and related chemistries); optimize reaction conditions, purification, and labeling efficiency from first principles
• Develop homogeneous immunoassays (TR-FRET, HTRF, AlphaLISA, MSD, and/or ELISA) for analyte detection; own the full development cycle from reagent selection and antibody pairing through format optimization and matrix validation
• Lead independent antibody screening campaigns to identify optimal capture/detection pairs; apply structured DOE approaches to optimize reagent concentrations, buffer formulations, and assay window
• Conduct routine assay validation experiments, including precision, accuracy, linearity, and range determination
• Prepare biological samples, reagents, and buffers according to SOPs
• Operate and maintain laboratory equipment, including plate readers, liquid handlers, and analytical instruments
• Independently diagnose and resolve assay performance failures; apply root-cause analysis to reagent, buffer, and instrument variables and propose data-driven corrective actions
• Support antibody screening and characterization activities
• Assist with benchmarking studies comparing assay performance to competitor products

Data Management & Documentation

• Maintain detailed, accurate, and organized laboratory notebooks documenting all experimental procedures and observations
• Analyze experimental data using GraphPad Prism, Excel, or similar software
• Generate clear data summaries, graphs, and tables for internal reports and presentations
• Contribute to technical reports and validation documents
• Assist in drafting sections of SOPs and user manual protocols
• Ensure all documentation meets company quality standards and regulatory requirements

Collaboration & Learning

• Work collaboratively with Senior Scientist and other team members to support project timelines
• Participate in team meetings and provide updates on experimental progress
• Communicate experimental results and technical challenges effectively to the supervisor
• Actively seek learning opportunities to develop technical skills in bioconjugation and immunoassay development
• Support cross-functional activities with Manufacturing, Quality, and Marketing teams as needed
• Participate in training programs to enhance scientific and professional development

Compliance & Safety

• Adhere to all site employee health and safety (EHS) and IT security requirements
• Demonstrate and promote the company vision and values
• Maintain regular attendance and punctuality
• Conduct all activities in a safe and efficient manner
• Perform other duties as assigned
• Meet project deadlines and adjust work hours as needed to support team objectives

Here is who and what we are are looking for in the ideal candidate:

Education/Experience (BMQ)

• BS/MS in chemistry, biochemistry, biology, or related discipline with 3–7 years of hands-on industrial experience developing immunoassays from scratch (ELISA, MSD, TR-FRET/HTRF, AlphaLISA, or equivalent); experience must include reagent selection, antibody screening, and quantitative assay optimization — not solely protocol execution
• Demonstrated experience independently developing and validating immunoassays — including reagent pair selection, signal-to-noise optimization, and characterization studies — with a verifiable track record of assays taken from concept to validated format
• Solid understanding of antibody-antigen binding kinetics, epitope considerations for sandwich vs. competitive immunoassay design, and the impact of protein biochemistry on assay performance
• Familiarity with aseptic technique and cell culture is a plus

Ability and/or Skills (BMQ)

• Strong laboratory skills with attention to detail and accuracy
• Basic proficiency in data analysis using Excel; familiarity with GraphPad Prism or similar software is a plus
• Good organizational and time management skills with the ability to balance multiple tasks
• Ability to design experiments from first principles, generate and test hypotheses, and translate results into actionable next steps — not limited to following pre-written protocols
• Strong work ethic with demonstrated reliability and accountability
• Eagerness to learn new techniques and acquire new scientific knowledge
• Good verbal and written communication skills
• Team player with positive attitude and willingness to collaborate
• Ability to work independently on assigned tasks while knowing when to seek guidance
• Comfortable working in a fast-paced laboratory environment with defined deadlines

Additional Preferences

• Experience developing assays in two or more immunoassay platforms (e.g., ELISA, MSD/ECL, TR-FRET/HTRF, AlphaLISA, Luminex); cross-platform familiarity is a strong differentiator
• Hands-on bioconjugation experience beyond kit use: NHS-ester, maleimide, aldehyde, or click-chemistry conjugation of small molecules, haptens, or fluorophores to antibodies or proteins, including optimization of degree of labeling (DOL) and purification
• Hands-on experience with multi-channel pipettes, automated liquid handlers, and plate readers
• Familiarity with time-resolved fluorescence or FRET-based detection principles (TR-FRET/HTRF, LANCE, or AlphaLISA); experience with plate reader instrumentation for fluorescence or luminescence readouts (e.g., PHERAstar, EnVision, or equivalent)
• Academic or industrial research experience in drug discovery, diagnostics, or related areas
• Experience maintaining detailed laboratory notebooks and documentation
• Applied experience with Design of Experiments (DOE) for reagent concentration and buffer optimization, not merely theoretical familiarity
• Experience presenting research findings in laboratory meetings or scientific conferences
• Demonstrated problem-solving skills and scientific curiosity
• Proficiency with Microsoft Office Suite (Word, Excel, PowerPoint)

Salary Range: $95,000 - $125,000/yr. 

• Excellent full time benefits including comprehensive medical coverage, dental, and vision options
• Life and disability insurance
• 401(k) with company match
• Paid vacation and holidays

Eurofins USA Discovery Services is a Disabled and Veteran Equal Employment Opportunity employer.