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Job Title:

Research Scientist - College of Medicine | Surgery

Department:

Medicine | Surgical Oncology

The Ohio State University College of Medicine and the Wexner Medical Center seek Bioinformatics Scientist to join the Department of Surgery.

Position Overview

The Division of Surgical Oncology, Department of Surgery at The Ohio State University Wexner Medical Center is seeking an exceptional Bioinformatics Scientist to support and advance translational and clinical research programs, with a particular focus on cancer genomics and high-dimensional data analysis. The successful candidate will work closely with multidisciplinary teams of clinicians, basic scientists, and data scientists to analyze and interpret large-scale datasets, including next-generation sequencing (NGS), transcriptomics, epigenomics, and other multi-omic platforms.

This individual will play a central role in the development, implementation, and optimization of bioinformatics pipelines; integration of clinical and molecular datasets; and generation of insights that inform biomarker discovery, therapeutic targeting, and clinical trial design. The position is ideal for candidates with strong computational expertise, scientific curiosity, and a collaborative mindset.

The Bioinformatics Scientist will contribute to ongoing institutional initiatives including biorepository efforts, precision oncology programs, and investigator-initiated clinical trials. Opportunities exist for independent and collaborative research, authorship, and grant development.

Key Responsibilities

Develop, implement, and maintain bioinformatics pipelines for analysis of high-throughput sequencing data (e.g., DNA-seq, RNA-seq, single-cell sequencing, spatial transcriptomics)
Perform integrative analyses of genomic, transcriptomic, and clinical datasets
Collaborate with clinical and laboratory investigators to design studies and interpret results
Support biomarker discovery and molecular subtyping efforts
Contribute to grant applications, manuscripts, and presentations
Ensure reproducibility and documentation of computational workflows
Maintain data integrity and compliance with institutional and regulatory standards
Provide mentorship and training to trainees and research staff as appropriate

Requirements

PhD in Bioinformatics, Computational Biology, Computer Science, Biostatistics, or a related field
Demonstrated experience with high-throughput sequencing data analysis
Proficiency in programming languages (e.g., Python, R) and bioinformatics tools
Experience with genomic data platforms (e.g., Illumina, 10x Genomics)
Familiarity with statistical modeling and machine learning approaches
Strong record of collaborative research and/or publications
Excellent communication and organizational skills
Experience with cancer genomics and translational oncology research
Experience integrating clinical and molecular datasets
Familiarity with cloud computing environments and high-performance computing clusters

Additional Information:

Location:

Biomedical Research Tower (0112)

Position Type:

Regular

Scheduled Hours:

Shift:

First Shift

Final candidates are subject to successful completion of a background check. A drug screen or physical may be required during the post offer process.

Thank you for your interest in positions at The Ohio State University and Wexner Medical Center. Once you have applied, the most updated information on the status of your application can be found by visiting the Candidate Home section of this site. Please view your submitted applications by logging in and reviewing your status. For answers to additional questions please review the frequently asked questions.

The university is an equal opportunity employer, including veterans and disability.