AbbVie's Local Delivery and Translational Science group seeks a Senior Scientist II/Principal Research Scientist I to lead translational science activities across the eyecare therapeutic portfolio. The successful candidate will drive program execution from preclinical development through early clinical translation in close collaboration with internal teams and external research partners.

Responsibilities

Serve as translational science lead and primary scientific representative across a diverse, multi-program eyecare development portfolio spanning preclinical through early clinical stages
Apply computational and data science approaches to synthesize and interpret biological datasets, generating evidence-based insights to support portfolio evaluation and program decision-making
Oversee preclinical study design, data review, and interpretation in collaboration with internal study teams, ensuring scientific rigor and alignment with program objectives
Develop translational plans that map preclinical evidence to early clinical decision points, ensuring continuity across development stages
Coordinate external research partnerships with CROs, academic collaborators, and biotech partners, including data management and scientific communication
Serve as scientific author for regulatory briefing documents and cross-functional program summaries
Synthesize input from drug delivery, clinical pharmacology, regulatory affairs, and business development to inform integrated program plans
Present scientific findings and program-level summaries to internal leadership and at external scientific meetings
Apply scientific judgment and analytical rigor to evaluate eyecare therapeutic candidates and inform portfolio prioritization and asset advancement decisions

Qualifications

Senior Scientist II Qualifications: PhD with 4+ years, Master's with 10+ years, or Bachelor's with 12+ years of relevant experience in a biological, biomedical, computational biology, or related life science discipline
Principal Research Scientist I Qualifications: PhD with 6+ years, Master's with 12+ years, or Bachelor's with 14+ years of relevant experience in a biological, biomedical, computational biology, or related life science discipline
Therapeutic area experience in ophthalmology, including familiarity with retinal disease biology and multiple treatment modalities
Proficiency in scientific programming (Python, R, or equivalent) for analysis and visualization of complex biological datasets
Experience with in vivo preclinical studies, including disease model development, study oversight, and interpretation of pharmacodynamic and efficacy endpoints
Track record of effective cross-functional collaboration in a matrixed pharmaceutical or biotechnology environment
Strong scientific communication skills, including preparation of technical documents and presentations to diverse audiences

Preferred Qualifications

Experience presenting scientific findings to external advisory boards, regulatory bodies, or equivalent forums
Familiarity with the translational development considerations for novel or emerging ophthalmic therapeutic approaches
Experience developing or applying translational biomarker strategies in preclinical or early clinical settings

Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law:

The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location, and we may ultimately pay more or less than the posted range. This range may be modified in the future.
We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees.
This job is eligible to participate in our long-term incentive programs.

Note: No amount of pay is considered to be wages or compensation until such amount is earned, vested, and determinable. The amount and availability of any bonus, commission, incentive, benefits, or any other form of compensation and benefits that are allocable to a particular employee remains in the Company's sole and absolute discretion unless and until paid and may be modified at the Company’s sole and absolute discretion, consistent with applicable law.

AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community.  Equal Opportunity Employer/Veterans/Disabled.

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