Downstream Development Engineer – Pilot Operations

The Downstream Development Engineer supports Pilot Lab operations bridging lab‑scale development and full‑scale manufacturing. This lab‑based role performs downstream purification activities, analyzes process data, and partners closely with Process Development and Manufacturing Sciences to support tech transfer.

Key Responsibilities

• Execute non‑GMP downstream purification at pilot scale (50–1000 L), including chromatography, UF/DF, TFF, and filtration.
• Support process development, troubleshooting, material supply runs, and demonstration campaigns.
• Track materials and samples; coordinate with vendors and internal teams.
• Record, analyze, and interpret process data; present findings and propose solutions.
• Contribute to SOPs, batch records, reports, and tech transfer documentation.
• Evaluate and integrate new pilot‑scale technologies and digital tools to improve efficiency.

• Bachelor’s in Chemistry, Biology, Engineering, or related field with 2+ years industry experience; or Master’s degree.
• Required: hands-on downstream purification experience.
• Preferred: experience with AKTA systems and Unicorn software.
• Experience working in a pilot plant or non‑GMP environment (50–1000 L scale).
• Strong analytical, problem‑solving, communication, and documentation skills.
• Ability to lift 25 lbs, stand for extended periods, and wear required PPE.
• Authorization to work in the United States indefinitely without restriction or sponsorship.

What to Expect in the Hiring Process:

• 10-15 Minute Phone Interview with Region Recruiter
• 45-60 Minute Virtual Interview with Manager and/or Group Leader
• 45-60 Minute Onsite to Meet the Team 

The position is Full Time, Monday-Friday, 8am-5pm. Candidates currently living within a commutable distance of Lexington, MA, are encouraged to apply.

What We Offer:

• Excellent full-time benefits, including comprehensive medical coverage, dental, and vision options
• Life and disability insurance
• 401(k) with company match
• Paid vacation and holidays
• Yearly goal-based bonus & eligibility for merit-based increases
• Hourly rate is between $30-34

Eurofins USA PSS Insourcing Solutions is a Disabled and Veteran Equal Employment Opportunity employer.