Research Lab Technician I

Site: The Brigham and Women's Hospital, Inc.

 

Mass General Brigham relies on a wide range of professionals, including doctors, nurses, business people, tech experts, researchers, and systems analysts to advance our mission. As a not-for-profit, we support patient care, research, teaching, and community service, striving to provide exceptional care. We believe that high-performing teams drive groundbreaking medical discoveries and invite all applicants to join us and experience what it means to be part of Mass General Brigham.

 

Job Summary

Under general supervision of Principal Investigator, and in accordance with established hospital policies and procedures, provides the technical support that is needed to support the activities of the Specialized Histopathology Core Laboratory. Responsible for performance of tests that rely on histologic, molecular cytogenetic, immunohistochemical, and in situ methods. Calculates, transcribes and analyzes data using basic statistics.
This laboratory is primarily interested in the pathology of neurodegenerative disease.
A position is open for a full-time research assistant in the Department of Pathology at Brigham and Women’s Hospital. The candidate will conduct research utilizing ultrasensitive seed amplification assays (SAA) alongside ultrasenstivie single molecule array (Simoa) and Molecular On-bead Signal Amplification for Individual Counting (MOSAIC) assays. Specific applications may include, but are not limited to, the protein aggregation of recombinantly expressed disordered proteins seeded with patient cerebral-spinal fluid or other bio-fluids using assays developed using existing SAA and Simoa/MOSAIC technology or the development of new diagnostic techniques. The candidate will work very independently, under general supervision, to perform experiments and measure biomarkers which are undetectable using conventional methods. Research conducted by the candidate in collaboration with the Research Team will provide new insights into various diagnostics and treatments and will address underlying biological questions.

1. Independently performs routine and non-routine experiments which are moderate to complex. Experimental work may include preparing reagents and evaluating binding reagent viability in assay platform, expressing and purifying protein from E. Coli, visualizing protein aggregates using fluorescence microscopy, and generating and developing microfluidic and droplet microfluidic encapsuolation techniques.
2. Calculate, transcribes and analyzes data using moderate to advanced statistical techniques.
3. Performs literature searches, prepares presentations and progress reports, and assists in preparing manuscripts for publication. Corresponds and communicates progress professionally with collaborators and scientific community.
4. In collaboration with PI or Research Manager, establishes new and modifies existing research techniques.
5. Coordinates schedule of tests and procedures. Documents experimental work accurately and in detail.
6. Coordinates lab activities such as bio-safety trainings.
7. Assists in the orientation and training of new staff.
8. Ordering and inventory of laboratory supplies.
9. All other duties as assigned.

 

Education
Bachelor's Degree Biological/physical science required.

Can this role accept experience in lieu of a degree?
Yes

•      Sound analytical and organizational skills

•      High degree of computer literacy.

•      Requires good oral and written communication skills

•      Must be able to logically and effectively structure tasks and set priorities.

•      Ability to identify potential problems and trouble-shoot solutions.

•      Demonstrated ability to analyze data statistically and to logically present it.

• Some prior research preferred but not essential.

 

Additional Job Details (if applicable)

 

Onsite

 

60 Fenwood Road

 

40

 

Regular

 

Day (United States of America)

 

Pay Range

$ - $29.01/Hourly

 

 

Grade

5

 

At Mass General Brigham, we believe in recognizing and rewarding the unique value each team member brings to our organization. Our approach to determining base pay is comprehensive, and any offer extended will take into account your skills, relevant experience if applicable, education, certifications and other essential factors. The base pay information provided offers an estimate based on the minimum job qualifications; however, it does not encompass all elements contributing to your total compensation package. In addition to competitive base pay, we offer comprehensive benefits, career advancement opportunities, differentials, premiums and bonuses as applicable and recognition programs designed to celebrate your contributions and support your professional growth. We invite you to apply, and our Talent Acquisition team will provide an overview of your potential compensation and benefits package.

 

2200 The Brigham and Women's Hospital, Inc. is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religious creed, national origin, sex, age, gender identity, disability, sexual orientation, military service, genetic information, and/or other status protected under law. We will ensure that all individuals with a disability are provided a reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. To ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Veteran’s Readjustment Act of 1974, and Title I of the Americans with Disabilities Act of 1990, applicants who require accommodation in the job application process may contact Human Resources at (857)-282-7642.

 

Mass General Brigham Competency Framework