The Opportunity
We seek a Senior Scientist I, Analytical Development to join an experienced, fast-paced and collaborative team. This position will be primarily responsible for supporting characterization of AbbVie’s mRNA-based targeted lipid nanoparticles (tLNPs) pipeline. This role will focus on executing testing methods for characterizing mRNA/tLNPs and supporting development of new tLNP characterization methods. Working collaboratively across the discovery research team, this position will support process/product characterization, expansion of the mRNA/tLNP pipeline, method development, and platform development.

Responsibilities & Duties:

Independently perform icIEF, HPLC, CE, and plate-based assay testing of mRNA and tLNP products for characterizing content, purity/impurities, and integrity
Support development of novel nanoparticle characterization techniques, including but not limited to icIEF, SEC, MALS, CZE, LC-MS, etc
Re-optimize analytical methods to support new programs and platform improvements
Improve routine assay efficiency through automation and assay/workflow improvements
Author technical reports and documents as needed

Bachelors, Masters, or Ph.D. in Analytical Chemistry typically with a minimum of 10 (BS), 8 (MS), or 0 (Ph.D.) years related industry experience.
Strong technical background in analytical chemistry, excellent analytical problem-solving skills. Capable of independently developing and troubleshooting analytical methods.
Degree in Biochemistry, Chemistry, Bioengineering, Chemical Engineering or related field with experience testing and developing analytical characterization methods for biologics (e.g. antibodies, mRNA, etc) is required.
Experience with nanoparticle and/or small molecule characterization is preferred
Demonstrate creative 'out of the box' thinking to solve difficult problems
Experience with icIEF, HPLC, Capillary Electrophoresis (CE), and plate-based assays required
Proficiency authoring and reviewing technical reports
Strong communication skills, both written and verbal, with a demonstrated capacity to thrive in collaborative, team-driven environments.

Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law:

The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this roleat the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on manyfactors including geographic location, and we may ultimately pay more or less than the posted range. This range may be modified in the future.
We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees.
This job is eligible to participate in our short-term incentive programs.

Note: No amount of pay is considered to be wages or compensation until such amount isearned, vested, and determinable. The amount and availability of any bonus, commission, incentive, benefits, or any other form of compensation and benefits that areallocable to a particular employee remains in the Company's sole and absolute discretion unless and until paid and may be modified at the Company’s sole and absolutediscretion, consistent with applicable law.

AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community.  Equal Opportunity Employer/Veterans/Disabled.

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