Sr. Scientist, Mass Spectrometry

Job Description

The Analytical Enabling Capabilities organization in West Point, PA is seeking a motivated scientist with technical expertise in mass spectrometry-based protein, protein conjugation or oligonucleotides or polysaccharide characterization. In addition to mass spectrometry skills, we are also seeking candidates with strong proteomics and data science skills.

The successful candidate is expected to independently conduct mass spectrometry experiments to support multiple vaccines programs, represent the team in cross-functional teams and develop new methods to solve current industry challenges. The work requires documenting experiments in electronic laboratory notebooks, authoring summaries to inform stakeholders, as well as presenting at seminars and publishing in scientific journals. The candidate with the right skills will also participate in optimizing our sample preparation, data processing and reporting strategies.

Primary Responsibilities

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Perform LC-MS based assays including peptide mapping, intact mass, native mass spectrometry, proteomics, higher order structure, and host cell protein analysis or oligonucleotides or polysaccharide characterization for vaccines programs.

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Represent the mass spectrometry group in project teams.

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Author technical reports and scientific presentations.

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Explore and develop new technologies applicable to our field.

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Perform data processing with Genedata or other biopharma data interpretation software.

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Demonstrate effective multitasking, prioritization and problem-solving skills in the planning and execution of experiments.

Education Requirements

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Ph.D. in Analytical Chemistry or Biological Sciences in the field of mass spectrometry

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Candidates with a MS degree and 4+ years, or BS degree and 7+ years of relevant experience will also be considered.

Required Experience and Skills

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Experience conducting mass spectrometry and proteomics experiments, including sample preparation and optimization, mass spectrometer operation and maintenance, and data interpretation and analysis.

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Experience with Thermo, Waters, and Sciex instruments.

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Familiarity with Genedata or other biopharma MS software.

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Excellent verbal and written communication skills, as demonstrated through high impact scientific publications and presentations.

Preferred Experience and Skills

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Experienced in higher order structure MS or proteomics

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Familiarity with electronic laboratory notebook applications and good documentation practices.

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Good understanding of vaccines development.

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Experience characterizing vaccines or recombinant proteins.

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Experience with protein conjugation, oligonucleotides or polysaccharide characterization.

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Familiarity with R programming language for data processing, statistics and visualization.

Required Skills

Liquid Chromatography-Mass Spectrometry (LC-MS), Mass Spectrometry (MS), Peptide Mapping, Protein Mass Spectrometry, Proteomics, Tandem Mass Spectrometry, Vaccine Development

Preferred Skills

Current Employees apply HERE

Current Contingent Workers apply HERE

US and Puerto Rico Residents Only

Our company is committed to inclusion, ensuring that candidates can engage in a hiring process that exhibits their true capabilities. Please click here if you need an accommodation during the application or hiring process.

As an Equal Employment Opportunity Employer, we provide equal opportunities to all employees and applicants for employment and prohibit discrimination on the basis of race, color, age, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or other applicable legally protected characteristics. As a federal contractor, we comply with all affirmative action requirements for protected veterans and individuals with disabilities. For more information about personal rights under the U.S. Equal Opportunity Employment laws, visit:

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The salary range for this role is

$117,000.00 - $184,200.00

This is the lowest to highest salary we in good faith believe we would pay for this role at the time of this posting. An employee’s position within the salary range will be based on several factors including, but not limited to relevant education, qualifications, certifications, experience, skills, geographic location, government requirements, and business or organizational needs.

The successful candidate will be eligible for annual bonus and long-term incentive, if applicable.

We offer a comprehensive package of benefits. Available benefits include medical, dental, vision healthcare and other insurance benefits (for employee and family), retirement benefits, including 401(k), paid holidays, vacation, and compassionate and sick days. More information about benefits is available at https://jobs.merck.com/us/en/compensation-and-benefits .

You can apply for this role through https://jobs.merck.com/us/en (or via the Workday Jobs Hub if you are a current employee). The application deadline for this position is stated on this posting.

San Francisco Residents Only: We will consider qualified applicants with arrest and conviction records for employment in compliance with the San Francisco Fair Chance Ordinance

Los Angeles Residents Only: We will consider for employment all qualified applicants, including those with criminal histories, in a manner consistent with the requirements of applicable state and local laws, including the City of Los Angeles’ Fair Chance Initiative for Hiring Ordinance

Search Firm Representatives Please Read Carefully Merck & Co., Inc., Rahway, NJ, USA, also known as Merck Sharp & Dohme LLC, Rahway, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company. No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place. Where agency agreements are in place, introductions are position specific. Please, no phone calls or emails.

Employee Status

Regular

Relocation

Domestic

VISA Sponsorship

Yes

Travel Requirements

No Travel Required

Flexible Work Arrangements

Not Applicable

Shift

Not Indicated

Valid Driving License

No

Hazardous Material(s)

N/A

Job Posting End Date

06/26/2026

*A job posting is effective until 11:59:59PM on the day BEFORE the listed job posting end date. Please ensure you apply to a job posting no later than the day BEFORE the job posting end date.

Requisition ID: R396083