Scientist I, In Vivo Pharmacology

Job Description:

The Discovery Neuroscience In Vivo Pharmacology group in Cambridge, Massachusetts, is seeking a highly skilled and self-motivated scientist to join a dynamic team supporting target identification, validation, PK/PD and efficacy studies. The ideal candidate will also have people and study management experience, as well as experience in independently running complex experiments.

Key Responsibilities:

Responsible for design and implementation of in vivo testing of multi specific biologics, small molecules, and siRNAs to support projects in the areas of Alzheimer’s and Parkinson’s disease
Identify and solve technical problems independently, implement new assays and workflows
Mentor junior scientists providing scientific and technical leadership in the design and execution of in vivo and ex vivo efficacy assessments
Ensure consistency and quality of technical reports
Collaborate with colleagues at various AbbVie sites
Present original work internally across departments and at internal and external scientific conferences; may author or co-author peer-reviewed scientific papers or patents.

Minimum Qualifications:

BSc or MS in Neuroscience, Biological Sciences, Pharmacology, or related discipline with typically 5+ (BSc), or 3+ (MS) years of experience in industry and/or academia
Proven track record of working in multidisciplinary in vivo pharmacology teams
Experience with in vivo models of neurodegeneration, particularly with models of Alzheimer’s and Parkinson’s Disease
Proven track record in characterizing complex biotherapeutics in vivo (biologics, small molecules, siRNA)
Excellent organizational skills and the ability to manage multiple projects simultaneously
Demonstrated ability to collaborate effectively in a dynamic, cross-functional matrix environment
Candidate must be a goal-oriented team player with excellent verbal and written communication skills and strong “can-do” attitude

Preferred Qualifications:

Background in receptor and / or transporter biology
Background in brain barriers biology
Experience with ex vivo readouts including immunohistochemistry and biochemistry (ELISA, WB)
Experience with image analysis

Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law:

The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this roleat the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on manyfactors including geographic location, and we may ultimately pay more or less than the posted range. This range may be modified in the future.
We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees.
This job is eligible to participate in our short-term incentive programs. Note: No amount of pay is considered to be wages or compensation until such amount isearned, vested, and determinable. The amount and availability of any bonus, commission, incentive, benefits, or any other form of compensation and benefits thatare allocable to a particular employee remains in the Company's sole and absolute discretion unless and until paid and may be modified at the Company’s sole andabsolute discretion, consistent with applicable law.

AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community.  Equal Opportunity Employer/Veterans/Disabled.

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